CSTA, 1-98aa, Human

Proteins, Recombinant
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Product Name CSTA, 1-98aa, Human
Background CSTA, also known as Stefin A, is thiol protease inhibitors that form complexes with papain and the cathepsins B, H and L. The protein is one of the precursor proteins of the cornified cell envelope in keratinocytes and plays a role in epidermal development and maintenance. CSTA is thought to be a tumor suppressor, since an inverse correlation seems to exist between the level of CSTA and tumor progression, in several malignancies Recombinant human CSTA protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
Synonyms Cystatin-A, STF1, STFA
Species Human
Molecular Weight 24.0 kDa (211aa) confirmed by MALDI-TOF
Concentration 0.5 mg/ml (determined by Bradford assay)
Form Liquid, in 10mM sodium citrate (pH 3.5) containing 40% glycerol
Purity > 95 % by SDS-PAGE
Applications SDS-PAGE
NCBI Accession # NP_005204
Host E.coli
Tag His-tag
Storage Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
Intended Use For Research Use Only
References Takai T., et al. (2009) J Immunol. 183(12):7958-65.
Sinha AA., et al. (2008) Anticancer Res. 28(4B):2271-7.

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