CtBP1, 1-440aa, Human

Catalog
01-1793-1
$0.00
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Proteins, Recombinant
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Product Name CtBP1, 1-440aa, Human
Background C-terminal-binding protein 1 isoform 1, also known as CtBP1, is expressed from embryo to adult. This protein binds to the C-terminus of adenovirus E1A. It is a cellular phosphoprotein that associates with various proteins and functions as a corepressor of transcription. Also, CtBP1 associates in complexes with histone deacetylases (HDAC), the G9a histone methyltransferase, and LSD1 histone demethylase illustrating its role in transcriptional repression. Recombinant human CtBP1 was expressed in E.coli and purified by using conventional chromatography techniques.
Synonyms BARS, C-terminal-binding protein 1 isoform 1 C terminal binding protein 1, CTBP, CTBP1, MGC104684.
Species Human
Amino Acid Sequence MGSSHLLNKG LPLGVRPPIM NGPLHPRPLV ALLDGRDCTV EMPILKDVAT VAFCDAQSTQ EIHEKVLNEA VGALMYHTIT LTREDLEKFK ALRIIVRIGS GFDNIDIKSA GDLGIAVCNV PAASVEETAD STLCHILNLY RRATWLHQAL REGTRVQSVE QIREVASGAA RIRGETLGII GLGRVGQAVA LRAKAFGFNV LFYDPYLSDG VERALGLQRV STLQDLLFHS DCVTLHCGLN EHNHHLINDF TVKQMRQGAF LVNTARGGLV DEKALAQALK EGRIRGAALD VHESEPFSFS QGPLKDAPNL ICTPHAAWYS EQASIEMREE AAREIRRAIT GRIPDSLKNC VNKDHLTAAT HWASMDPAVV HPELNGAAYR YPPGVVGVAP TGIPAAVEGI VPSAMSLSHG LPPVAHPPHA PSPGQTVKPE ADRDHASDQL
Molecular Weight 17.2 kDa (152aa), confirmed by MALDI-TOF.
Concentration 1 mg/ml (determined by Bradford assay)
Form Liquid, in 20 mM Tris-HCl buffer (pH8.0) containing 1mM DTT, 10% glycerol
Purity > 90% by SDS-PAGE
Applications SDS-PAGE
NCBI Accession # NP_001319
Storage Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
Intended Use For Research Use Only
References Izutsu K., et al. (2001) Blood. 97(9):2815-22.
Yu X., et al. (1998) J Biol Chem. 273:25388-25392.
Host E.coli
Tag His-tag

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