| Product Name | CXCL1, 25-96aa, Mouse |
|---|---|
| Description | CXCL1, also known as GROA or GRO-alpha, is a growth factor for melanoma cells and a chemotaxin for neutrophils. Similar to other alpha chemokines, this protein is potent neutrophil attractant and activator and is also active toward basophils. In addition, CXCL1 protein may be a therapeutic target as well as a diagnostic marker in ovarian cancer. Recombinant mouse CXCL1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques |
| Synonyms | Chemokine (C-X-C motif) ligand 1, GRO, GRO1, GROA, MGSA, SCYB1, GRO-alpha |
| Host | E.coli |
| Molecular Weight | 46.9 kDa (424aa), confirmed by MALDI-TOF |
| Amino Acid Sequence | MGSSHHHHHH SSGLVPRGSH MGSHMAPIAN ELRCQCLQTM AGIHLKNIQS LKVLPSGPHC TQTEVIATLK NGREACLDPE APLVQKIVQK MLKGVPK |
| Tag | His-tag |
| Reactivity | Mouse |
| Applications | SDS-PAGE |
| Form | Liquid, in 20mM Tris-HCl buffer (pH 8.0) containing 0.1M NaCl, 10% glycerol |
| Concentration | 0.25 mg/ml (determined by Bradford assay) |
| Purity | > 90% by SDS-PAGE |
| Storage | Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles. |
| References |
Sun,D.. et al. .(2011) Nat. Immunol. 12 (9), 853-860 Oka,M., et al. (2011) Lab. Invest. 91 (5), 711-718 |
| Supplier | ARP |
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