CXCL13, 23-109aa, Human

Catalog
01-P2437
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Proteins, Recombinant
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Product Name CXCL13, 23-109aa, Human
Background B lymphocyte chemoattractant, independently cloned and named Angie, is a CXC chemokine strongly expressed in the follicles of the spleen, lymph nodes, and Peyer's patches. It preferentially promotes the migration of B lymphocytes (compared to T cells and macrophages), apparently by stimulating calcium influx into, and chemotaxis of, cells expressing Burkitt's lymphoma receptor 1 (BLR-1). It may therefore function in the homing of B lymphocytes to follicles. Recombinant human CXCL13 protein, fused to His-tag at N-terminus, was expressed in E.coli
Synonyms Chemokine (C-X-C motif) ligand 13, ANGIE, ANGIE2, BCA-1, BCA1, BLC, BLR1L, SCYB13
Species Human
Amino Acid Sequence MGSSHHHHHH SSGLVPRGSH MGSVLEVYYT SLRCRCVQES SVFIPRRFID RIQILPRGNG CPRKEIIVWK KNKSIVCVDP QAEWIQRMME
VLRKRSSSTL PVPVFKRKIP
Molecular Weight 23.1kDa (209aa), confirmed by MALDI-TOF
(Molecular size on SDS-PAGE will appear higher)
Concentration 0.25 mg/ml (determined by Bradford assay)
Form Liquid, in 20mM Tris-HCl (pH8.0) containing 20% glycerol,
0.1M NaCl, 1mM DTT
Purity >85 % by SDS-PAGE
Applications SDS-PAGE
NCBI Accession # NP_006410
Host E.coli
Tag His-tag
Storage Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
Intended Use For Research Use Only
References Gunn M.D., Ngo V.N.. et al. (1998). Nature 391:799-803

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