DCAF7, 19-295aa, Human

Catalog
01-P1177
$0.00
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Proteins, Recombinant
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Product Name DCAF7, 19-295aa, Human
Background DCAF7, also known as DDB1-and CUL4-associated factor, involved in craniofacial development. This protein acts upstream of the EDN1 pathway and is required for formation of the upper jaw equivalent, the palatoquadrate. The activity required for EDN1 pathway function differs between the first and second arches. This protein associates with DIAPH1 and controls GLI1 transcriptional activity. This protein could be involved in normal and disease skin development. Recombinant human DCAF7 protein, fused to His-tag at N-terminus, was expressed in E.coli and denatured using detergent during conventional chromatography purification process.
Synonyms DDB1-and CUL4-associated factor 7, AN11, HAN11, SWAN-1, WDR68
Species Human
Amino Acid Sequence MGSSHHHHHH SSGLVPRGSH MVYAMNWSVR PDKRFRLALG SFVEEYNNKV QLVGLDEESS EFICRNTFDH PYPTTKLMWI PDTKGVYPDL LATSGDYLRV WRVGETETRL ECLLNNNKNS DFCAPLTSFD WNEVDPYLLG TSSIDTTCTI WGLETGQVLG RVNLVSGHVK TQLIAHDKEV YDIAFSRAGG GRDMFASVGA DGSVRMFDLR HLEHSTIIYE DPQHHPLLRL CWNKQDPNYL ATMAMDGMEV VILDVRVPCT PVARLNNHRA CVNGIAWAPH SSCHICTAAD DHQALIWD
Molecular Weight 28.2 kDa (267aa), confirmed by MALDI-TOF
Concentration 1 mg/ml (determined by Bradford assay)
Form Liquid, in 20mM Tris-HCl buffer (pH 8.0) containing 10% glycerol, 2mM DTT.
Purity > 90% by SDS-PAGE
Applications SDS-PAGE
NCBI Accession # NP_005819
Host E.coli
Tag His-tag
Storage Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
Intended Use For Research Use Only
References Morita K., et al. (2006) J. Dermatol. Sci. 44:11-20
Jin J., et al. (2006) Mol. Cell. 23:709-721

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