DESI1, 1-168aa, Human

Catalog
01-P2242
$0.00
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Proteins, Recombinant
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Product Name DESI1, 1-168aa, Human
Background DESI1 belongs to the DeSI family and contains 1 PPPDE peptidase domain. This protein is a protease which deconjugates SUMO1, SUMO2 and SUMO3 from some substrate proteins and has isopeptidase but not SUMO-processing activity. DESI1 desumoylates ZBTB46. Recombinant human DESI1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
Synonyms Desumoylating isopeptidase 1, D15Wsu75e, DeSI-1, DESI2, DJ347H13.4, FAM152B, PPPDE2
Species Human
Amino Acid Sequence MGSSHHHHHH SSGLVPRGSH MGSMEPPNLY PVKLYVYDLS KGLARRLSPI MLGKQLEGIW HTSIVVHKDE FFFGSGGISS CPPGGTLLGP PDSVVDVGST EVTEEIFLEY LSSLGESLFR GEAYNLFEHN CNTFSNEVAQ FLTGRKIPSY ITDLPSEVLS TPFGQALRPL LDSIQIQPPG GSSVGRPNGQ S
Molecular Weight 29.5kDa (258aa) confirmed by MALDI-TOF
Concentration 0.5 mg/ml (determined by Bradford assay)
Form Liquid, in 20mM Tris-HCl buffer (pH 8.0) containing 0.15M NaCl, 10% glycerol, 1mM DTT
Purity > 85% by SDS-PAGE
Applications SDS-PAGE
NCBI Accession # NP_056519
Host E.coli
Tag His-tag
Storage Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
Intended Use For Research Use Only
References Briegel W., et al. (2004) Psychother. 32:107-115
Gothelf D., et al. (2008) Dev Disabil res Rev. 14:59-68

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