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|Product Name||Disulfide-bond isomerase (DsbC), Recombinant|
|Background||Recombinant Disulfide Oxidoreductase (rDsbA), produced from E.Coli is a periplasmic protein and thioredoxin superfamily member which introduces disulfide bonds directly into substrate proteins by donating the disulfide bond in its active-site Cys30-Pro31-His32-Cys33 to a pair of cysteines in substrate proteins. DsbA consists of 208 amino acids containing signal peptide(1-19 amino acids). Recombinant DsbA (residues 20-208) was expressed in E. coli and purified by using conventional chromatography techniques.|
|Synonyms||dsbC, xprA, Disulfide-bond isomerase (DsbC) E.Coli, Thiol:disulfide interchange protein dsbC, Disulfide-bond isomerase C Thiol:disulfide interchange protein dsbC .|
|Amino Acid Sequence||DDAAIQQTLA KMGIKSSDIQ PAPVAGMKTV LTNSGVLYIT DDGKHIIQGP MYDVSGTAPV NVTNKMLLKQ LNALEKEMIV YKAPQEKHVI TVFTDITCGY CHKLHEQMAD YNALGITVRY LAFPRQGLDS DAEKEMKAIW CAKDKNKAFD DVMAGKSVAP ASCDVDIADH YVLGVQLGVS GTPAVVLSNG TLVPGYQPPK EMKEFLDEHQ KMTSGK|
|Molecular Weight||59.4kDa (549aa)|
|Concentration||1 mg/ml (determined by Bradford assay)|
|Form||Liquid, in 20mM Tris pH 8.0, 50mM NaCl, 1mM DTT|
|Purity||> 95% by SDS-PAGE|
|NCBI Accession #||YP_00145967|
|Storage||Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.|
|Intended Use||For Research Use Only|
|References||Peter W., et al. (2002). EMBO 21, 4774-4784
Laura Segatori., et al. (2004). PNAS 27, 10018-10023
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