DUSP13, 1-198aa Human

Catalog
01-P1654
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Proteins, Recombinant
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Product Name DUSP13, 1-198aa Human
Background DUSP13 (Dual specificity phosphatase 13) belongs to the protein-tyrosine phosphatase family. It cooperates with protein kinases to regulate cell proliferation and differentiation. DUSP13 is involved in the regulation of meiosis and/or differentiation of testicular germ cells during spermatogenesis. This protein exhibits intrinsic phosphatase activity towards both phospho-seryl/threonyl and -tyrosyl residues of myelin basic protein, with similar specific activities in vitro. Recombinant human DUSP13 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
Synonyms Dual specificity phosphatase 13, BEDP, DUSP13A, DUSP13B, MDSP, SKRP4, TMDP
Species Human
Amino Acid Sequence MGSSHHHHHH SSGLVPRGSH MGSHMDSLQK QDLRRPKIHG AVQASPYQPP TLASLQRLLW VRQAATLNHI DEVWPSLFLG DAYAARDKSK LIQLGITHVV NAAAGKFQVD TGAKFYRGMS LEYYGIEADD NPFFDLSVYF LPVARYIRAA LSVPQGRVLV HCAMGVSRSA TLVLAFLMIC ENMTLVEAIQ TVQAHRNICP NSGFLRQLQV LDNRLGRETG RF
Molecular Weight 46.6kDa (406aa) confirmed by MALDI-TOF
Concentration 1 mg/ml (determined by Bradford assay)
Form Liquid, in 20mM Tris-HCl buffer (pH 8.0) containing 0.1M NaCl, 10% glycerol,1mM DTT
Purity > 95% by SDS-PAGE
Applications SDS-PAGE
NCBI Accession # NP_057448
Host E.coli
Tag His-tag
Storage Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
Intended Use For Research Use Only
References Chen H.-H., et al. (2004) J. Biol. Chem. 279:41404-41413
Katagiri C, et al. (2011) Mol Cell Biochem. 352(1-2):155-62.

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