DUSP23, 1-150aa, Human

Proteins, Recombinant
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Product Name DUSP23, 1-150aa, Human
Background DUSP23, also known as low molecular mass dual specificity phosphatase 3(LDP-3), belongs to the protein-tyrosine phosphatase family. This protein is a protein phosphatase that mediates dephosphorylation of proteins phosphorylated on Tyr and Ser/Thr residues. In vitro, it can dephosphorylate p44-ERK1 (MAPK3) but not p54 SAPK-beta (MAPK10) in vitro. This protein able to enhance activation of JNK and p38(MAPK14). Recombinant human DUSP23 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
Synonyms Dual specificity protein phosphatase 23, DUSP25, LDP-3, MOSP, VHZ
Species Human
Molecular Weight 27.1 kDa (243aa), confirmed by MALDI-TOF
Concentration 1.0 mg/ml (determined by Bradford assay)
Form Liquid, in 20mM Tris-HCl buffer (pH8.0) containing 20% glycerol, 2mM DTT
Purity > 90% by SDS-PAGE
Applications SDS-PAGE
NCBI Accession # NP_060293
Host E.coli
Tag His-tag
Storage Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
Intended Use For Research Use Only
References Alonso A., et al. (2004) J. Biol. Chem. 279:35768-35774
WU Q, et al. (2004) Int J Biochem Cell Biol. 36(8):1542-53.

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