DYNLT1, 1-113aa, Human

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01-DYNL-T1
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Proteins, Recombinant
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Product Name DYNLT1, 1-113aa, Human
Background Dynein light chain Tctex-type 1, also known as DYNLT1, belongs to the dynein light chain Tctex-type family. DYNLT1 acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein is the major motor protein complex responsible for minus-end, microtubule-based motile processes. Each dynein complex consists of 2 heavy chains that have ATPase and motor activities, plus a group of accessory polypeptides. DYNLT1 is a dynein light chain involved in cargo binding. Recombinant human DYNLT1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
Synonyms Dynein light chain Tctex-type 1, CW-1, TCTEL1, tctex-1
Species Human
Amino Acid Sequence MGSSHHHHHH SSGLVPRGSH MEDYQAAEET AFVVDEVSNI VKEAIESAIG GNAYQHSKVN QWTTNVVEQT LSQLTKLGKP FKYIVTCVIM QKNGAGLHTA SSCFWDSSTD GSCTVRWENK TMYCIVSAFG LSI
Molecular Weight 45.1 kDa (432aa) confirmed by MALDI-TOF (Molecular weight on SDS-PAGE will appear higher)
Concentration 0.5 mg/ml (determined by BCA assay)
Form Liquid, in 20mM Tris-HCl buffer (pH8.0) containing 20% glycerol
Purity > 95% by SDS-PAGE
Applications SDS-PAGE
NCBI Accession # NP_006510
Host E.coli
Tag His-tag
Storage Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
Intended Use For Research Use Only
References Asai D J., et al. (2004) J Eukaryot Microbiol. 51:23-29.
He Y., et al. (2005) J Cell Biol. 168:697-703.

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