EBAG9, 28-213aa, Human, Recombinant

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01-2027
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Proteins, Recombinant
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Product Name EBAG9, 28-213aa, Human, Recombinant
Background Estrogen receptor binding site associated antigen 9, also known as EBAG9, is a type III transmembrane protein that is predominantly located in the Golgi. This protein is a tumor-associated antigen that is expressed at high frequency in a variety of cancers, such as advanced breast and prostate cancers. As the EBAG9 acts to inhibit the growth of receptor-binding cells and induced apoptosis of immune cells, cancer cells might evade immune surveillance. So immunodetection of EBAG9 expression can be a negative prognostic indicator. Recombinant human EBAG9 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
Synonyms EB9, PDAF, RCAS1, Estrogen receptor binding site associated antigen 9, EBAG9, Estrogen receptor binding site associated, antigen 9 BAG9, Cancer associated surface antigen, Cancer associated surface antigen RCAS1, EBAG 9, Estrogen receptor binding fragment associated gene 9 protein, PDAF, RCAS 1, RCAS1, Receptor binding cancer antigen expressed on SiSo cells.
Species Human
Amino Acid Sequence MGSSHHHHHH SSGLVPRGSH MRSGRGRKLS GDQITLPTTV DYSSVPKQTD VEEWTSWDED APTSVKIEGG NGNVATQQNS LEQLEPDYFK DMTPTIRKTQ KIVIKKREPL NFGIPDGSTG FSSRLAATQD LPFIHQSSEL GDLDTWQENT NAWEEEEDAA WQAEEVLRQQ KLADREKRAA EQQRKKMEKE AQRLMKKEQN KIGVKLS
Molecular Weight 41.6kDa (384aa)
Concentration 1 mg/ml (determined by Bradford assay)
Form Liquid, in 25 mM Tris-HCl, pH7.5, 100 mM NaCl, 5 mM DTT, 10%Glycerol.
Purity > 90% by SDS PAGE
Applications SDS-PAGE
NCBI Accession # NP_004206
Host E.coli
Tag His-tag
Storage Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
Intended Use For Research Use Only
References Kumagai J., et al.,(2009) Int J Cancer.124(4):816-26.
Yoshida S., et al.,(2008) J Rheumatol. 35(9):1716-22.

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