EXOSC4, 1-245aa, Human

Catalog
01-P2415
$0.00
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Proteins, Recombinant
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Product Name EXOSC4, 1-245aa, Human
Background EXOSC4, also known as fetuin-A, belongs to the fetuin class of plasma binding proteins. It is involved in several functions, such as endocytosis, brain development and the formation of bone tissue. It is commonly present in the cortical plate of the immature cerebral cortex and bone marrow hemopoietic matrix, and it has been postulated that it participates in the development of the tissues. It forms soluble complexes with calcium and phosphate and thus is a carrier of otherwise insoluble calcium phosphate. Recombinant human EXOSC4 protein, fused to His-tag at N-terminus, was expressed in E.coli.
Synonyms hRrp41p, p12A, RRP41, RRP41A, Rrp41p, SKI6, Ski6p
Species Human
Amino Acid Sequence MGSSHHHHHH SSGLVPRGSH MGSMAGLELL SDQGYRVDGR RAGELRKIQA RMGVFAQADG SAYIEQGNTK ALAVVYGPHE IRGSRARALP
DRALVNCQYS SATFSTGERK RRPHGDRKSC EMGLQLRQTF EAAILTQLHP RSQIDIYVQV LQADGGTYAA CVNAATLAVL DAGIPMRDFV
CACSAGFVDG TALADLSHVE EAAGGPQLAL ALLPASGQIA LLEMDARLHE DHLERVLEAA AQAARDVHTL LDRVVRQHVR EASILLGD
Molecular Weight 34.2 kDa (303aa) confirmed by MALDI-TOF
Concentration 1mg/ml (determined by Bradford assay)
Form Liquid, in 20mM Tris-HCl buffer (pH 8.0) containing 0.15M NaCl, 10% glycerol, 1mM DTT, 0.1mM PMSF
Purity > 85% by SDS-PAGE
Applications SDS-PAGE
NCBI Accession # NP_061910
Host E.coli
Tag His-tag
Storage Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
Intended Use For Research Use Only
References Osawa M. et al. (1997) Gene. 196:121-125.
Rizzu P. et al. (1995) Cytogenet Cell Genet.. 70:26-28.

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