FIBP, 1-364aa, Human

Catalog
01-P2145
$0.00
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Proteins, Recombinant
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Product Name FIBP, 1-364aa, Human
Background Acidic fibroblast growth factor intracellular-binding protein isoform a, also known as FIBP, is a member of Fibroblast growth factors (FGFs) represent a family. FGF activity influences development, adult tissue homeostasis, angiogenesis and cancer progression. FIBP is a 364 amino acid protein that binds to internalized FGF-1 and is thought to be involved in mitogenic function of FGF-1. FIBP localizes to the nucleus and is highly expressed in heart, skeletal muscle and pancreas and at lower levels in brain, placenta, liver and kidney. Recombinant human FIBP protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
Synonyms Acidic fibroblast growth factor intracellular-binding protein, FGFIBP, FIBP-1, FIBP1, aFGF intracellular-binding protein
Species Human
Amino Acid Sequence MGSSHHHHHH SSGLVPRGSH MGSMTSELDI FVGNTTLIDE DVYRLWLDGY SVTDAVALRV RSGILEQTGA TAAVLQSDTM DHYRTFHMLE RLLHAPPKLL HQLIFQIPPS RQALLIERYY AFDEAFVREV LGKKLSKGTK KDLDDISTKT GITLKSCRRQ FDNFKRVFKV VEEMRGSLVD NIQQHFLLSD RLARDYAAIV FFANNRFETG KKKLQYLSFG DFAFCAELMI QNWTLGAVGE APTDPDSQMD DMDMDLDKEF LQDLKELKVL VADKDLLDLH KSLVCTALRG KLGVFSEMEA NFKNLSRGLV NVAAKLTHNK DVRDLFVDLV EKFVEPCRSD HWPLSDVRFF LNQYSASVHS LDGFRHQALW DRYMGTLRGC LLRLYHD
Molecular Weight 15.6kDa (148aa), confirmed by MALDI-TOF
Concentration 0.25 mg/ml (determined by BCA assay)
Form Liquid, in 20mM Tris-HCl buffer (pH 8.0) containing 0.15M NaCl, 20% glycerol
Purity > 95% by SDS-PAGE
Applications SDS-PAGE
NCBI Accession # NP_942600
Host E.coli
Tag His-tag
Storage Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
Intended Use For Research Use Only
References Kolpakova E., et al. (1998) Biocham J. 336:213-222
Volkin D B., et al. (1996) Biotechnol. 9:181-217.

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