FKBP14, 20-211aa, Human

Proteins, Recombinant
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Product Name FKBP14, 20-211aa, Human
Background FKBP14, also known as 22 kDa FK506-binding protein, is an enzyme that accelerates the folding of proteins during protein synthesis. This protein contains two EF-hand domains and one PPIase FKBP-type domain. Truncation of the amino-terminus of FKBP14 greatly reduces peptidyl prolyl cis-trans isomerase activity, therefore suggesting that the PPIase FKBP-type domain must be located at the N-terminus. Recombinant human FKBP14 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography
Synonyms FKBP22, Peptidyl-prolyl cis-trans isomerase FKBP14, 22 kDa FK506 binding protein, FK506 binding protein 14 (22 kDa), FK506 binding protein 14, FKBP 22, FKBP22, Peptidyl prolyl cis trans isomerase, PPIase, Rotamase
Species Human
Molecular Weight 14.0kDa (128aa) confirmed by MALDI-TOF
Concentration 0.5 mg/ml (determined by Bradford assay)
Form Liquid, in 20mM Tris-HCl buffer (pH8.0) containing 20% glycerol, 2mM DTT, 100mM NaCl
Purity > 90% by SDS-PAGE
Applications SDS-PAGE
NCBI Accession # NP_060416
Host E.coli
Tag His-tag
Storage Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
Intended Use For Research Use Only
References Tremmel D., et al. (2007) J Mol Biol. 369(1):55-68.
Budiman C., et al. (2009) FEBS J. 276(15):4091-101.

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