FTL, 1-175aa, Human, Recombinant

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01-2030
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Proteins, Recombinant
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Product Name FTL, 1-175aa, Human, Recombinant
Background Ferritin is a large, iron-storage heteropolymeric protein composed of two subunit types, light (FTL) and heavy (FTH1) polypeptides, which is expressed in most kinds of cells and co-assemble in different proportion in a tissue-specific manner. Ferritin is composed of 24 self-assembled polypeptide subunits and is characterized by the capacity to remove Fe (II) from solution in the presence of oxygen. Recombinant human FTL was expressed in E.coli and purified by conventional chromatography techniques.
Synonyms Ferritin L subunit, Ferritin, light polypeptide 1, FTL, Ferritin, light polypeptide 1 Ferritin H subunit, Ferritin heavy chain like, Ferritin heavy polypeptide 1, Ferritin light chain like, Ferritin light polypeptide, Ferritin, heavy polypeptide, FTH, FTH1, FTL protein.
Species Human
Amino Acid Sequence MSSQIRQNYS TDVEAAVNSL VNLYLQASYT YLSLGFYFDR DDVALEGVSH FFRELAEEKR EGYERLLKMQ NQRGGRALFQ DIKKPAEDEW GKTPDAMKAA MALEKKLNQA LLDLHALGSA RTDPHLCDFL ETHFLDEEVK LIKKMGDHLT NLHRLGGPEA GLGEYLFERL TLKHD
Molecular Weight 16.5kDa (147aa), confirmed by MALDI-TOF.
Concentration 1 mg/ml (determined by Bradford assay)
Form Liquid, in 50 mM Tris pH 8.0 Molecular Weight: 16.5 kDa (147 aa)
Purity > 90% by SDS-PAGE
Applications SDS-PAGE
NCBI Accession # NP_000137
Host CHO Cell
Tag His-tag
Storage Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
Intended Use For Research Use Only
References Baraibar MA., et al. (2008) J. Biol. Chem, 283(46), 31679-89.
Santambrogio P., et al. (2000) Protein. Expr. Purif, 19(1), 212-8

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