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|Product Name||GSTO2, 1-243aa, Human|
|Background||Glutathione S-transferase omega 2, also known as GSTO2, belongs to the GST superfamily and may be involved in catalyzing the reaction of glutathione with a wide variety of organic compounds to form thioethers, a process that is essential for the metabolism and detoxification of a variety of xenobiotics and carcinogens. GSTO2 is related to GSTO1 and is expressed in a variety of tissues throughout the body where it functions to catalyze the conversion of RX and glutathione to HX and R-S-glutathione. Recombinant human GSTO2 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.|
|Synonyms||Glutathione S-transferase omega 2, bA127L20.1|
|Amino Acid Sequence||MGSSHHHHHH SSGLVPRGSH MGSMSGDATR TLGKGSQPPG PVPEGLIRIY SMRFCPYSHR TRLVLKAKDI RHEVVNINLR NKPEWYYTKH PFGHIPVLET SQCQLIYESV IACEYLDDAY PGRKLFPYDP YERARQKMLL ELFCKVPHLT KECLVALRCG RECTNLKAAL RQEFSNLEEI LEYQNTTFFG GTCISMIDYL LWPWFERLDV YGILDCVSHT PALRLWISAM KWDPTVCALL MDKSIFQGFL NLYFQNNPNA FDFGLC|
|Molecular Weight||13.4kDa (117aa), confirmed by MALDI-TOF|
|Concentration||1mg/ml (determined by Bradford assay)|
|Form||Liquid, in 20 mM Tris-HCl buffer, pH8.0, 40% glycerol, 3mM DTT, 200mM NaCl|
|Purity||> 85% by SDS-PAGE|
|NCBI Accession #||NP_899062|
|Storage||Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.|
|Intended Use||For Research Use Only|
|References||Chariyalertsak S., et al. (2009) Tumori. 95:739-743.
Andonova I E., et al. (2010) Treat. 121: 497-52.
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