GTF2B, 1-316aa, Human

Catalog
01-1758-2B
$0.00
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Proteins, Recombinant
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Product Name GTF2B, 1-316aa, Human
Background GTF2B, also known as transcription factor II B, is one of several general transcription factors that make up the RNA polymerase II preinitiation complex. It localizes to the nucleus where it forms a complex (the DAB complex) with transcription factors IID and IIA. The protein serves as a bridge between IID, the factor which initially recognizes the promoter sequence, and RNA polymerase II. It is involved in the selection of the transcription start site. Recombinant GTF2B protein was expressed in E.coli and purified by using conventional chromatography techniques.
Synonyms TF2B, TFIIB, General transcription factor IIB General transcription factor TFIIB, GTF2B, RNA polymerase II transcription factor IIB, S300 II, TF IIB, Transcription initiation factor IIB.
Species Human
Amino Acid Sequence MGSSHHHHHH SSGLVPRGSH MASTSRLDAL PRVTCPNHPD AILVEDYRAG DMICPECGLV VGDRVIDVGS EWRTFSNDKA TKDPSRVGDS QNPLLSDGDL STMIGKGTGA ASFDEFGNSK YQNRRTMSSS DRAMMNAFKE ITTMADRINL PRNIVDRTNN LFKQVYEQKS LKGRANDAIA SACLYIACRQ EGVPRTFKEI CAVSRISKKE IGRCFKLILK ALETSVDLIT TGDFMSRFCS NLCLPKQVQM AATHIARKAV ELDLVPGRSP ISVAAAAIYM ASQASAEKRT QKEIGDIAGV ADVTIRQSYR LIYPRAPDLF PTDFKFDTPV DKLPQL
Molecular Weight 24.9 kDa (225aa), confirmed by MALDI-TOF.
Concentration 1 mg/ml (determined by Bradford assay)
Form Liquid, in 20mM Tris-HCl buffer (pH 8.0) containing 10% glycerol, 1mM DTT, 0.1 M NaCl.
Purity > 90% by SDS-PAGE
Applications SDS-PAGE
NCBI Accession # NP_001505
Host E.coli
Storage Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
Intended Use For Research Use Only
References Ing N.H., et al. (1992) J. Biol. Chem. 267:17617-17623.
Bushnell, David A, et al. (2004) Science. 303(5660):983-8.

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