HMOX2, 1-264aa, Human

Category: Proteins
Catalog
01-1775-2
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Product Name HMOX2, 1-264aa, Human
Description HMOX2 is microsomal enzyme that cleave heme ring at the alpha methane bridge to produce the antioxidant biliverdin, inorganic iron and carbon monoxide. Biliverdin is subsequently converted to bilirubin by bilibverdin reductase. This protein appears to be constitutively expressed in mammalian tissues. HMOX2 is involved in the production of carbon monoxide (CO) in brain, where CO is thought to act as a neurotransmitter. Recombinant HMOX2 protein was expressed in E.coli and purified by using conventional chromatography techniques.
Synonyms , Heme oxygenase 2 Heme oxygenase (decycling) 2, Heme oxygenase (decyclizing) 2, HMOX 2, HMOX2 protein, HO 2, HO2
Host E.coli
Molecular Weight 16 kDa (137aa), confirmed by MALDI-TOF.
Amino Acid Sequence MSAEVETSEG VDESEKKNSG ALEKENQMRM ADLSELLKEG TKEAHDRAEN TQFVKDFLKG NIKKELFKLA TTALYFTYSA LEEEMERNKD HPAFAPLYFP MELHRKEALT KDMEYFFGEN WEEQVQCPKA AQKYVERIHY IGQNEPELLV AHAYTRYMGD LSGGQVLKKV AQRALKLPST GEGTQFYLFE NVDNAQQFKQ LYRARMNALD LNMKTKERIV EEANKAFEYN MQIFNELDQA GSTLARETLE DGFPVHDGKG DMRK
Tag His-tag
Reactivity Human
Applications SDS-PAGE
Form Liquid, in 20mM Tris-HCl buffer (pH8.0) containing 20% glycerol 0.2M NaCl
Concentration 1 mg/ml (determined by Bradford assay)
Purity > 90% by SDS-PAGE
Storage Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
References Baranano DE., et al. (2001) Proc Natl Acad Sci U S A. 98(20):10996-1002.
Dore S., et al. (2002) Free Radic Biol Med. 32(12):1276-82.
Supplier ARP

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