IL13RA2, 27-343aa, Human

Catalog
01-P2139
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Proteins, Recombinant
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Product Name IL13RA2, 27-343aa, Human
Background IL13RA2 is closely related to Il13RA1, a subuint of the interleukin 13 receptor complex. This protein binds IL13 with high affinity, but lacks cytoplasmic domain, and does not appear to function as a signal mediator. It is reported to play a role in the internalization of IL13. Recombinant human IL13RA2 protein, fused to His-tag at N-terminus, was expressed in E.coli.
Synonyms interleukin-13 receptor subunit alpha-2 precursor, CD213A2, CT19, IL-13R, IL13BP
Species Human
Amino Acid Sequence MGSSHHHHHH SSGLVPRGSH MGSDTEIKVN PPQDFEIVDP GYLGYLYLQW QPPLSLDHFK ECTVEYELKY RNIGSETWKT IITKNLHYKD GFDLNKGIEA KIHTLLPWQC TNGSEVQSSW AETTYWISPQ GIPETKVQDM DCVYYNWQYL LCSWKPGIGV LLDTNYNLFY WYEGLDHALQ CVDYIKADGQ NIGCRFPYLE ASDYKDFYIC VNGSSENKPI RSSYFTFQLQ NIVKPLPPVY LTFTRESSCE IKLKWSIPLG PIPARCFDYE IEIREDDTTL VTATVENETY TLKTTNETRQ LCFVVRSKVN IYCSDDGIWS EWSDKQCWEG EDLSKKTLLR
Molecular Weight 14.3kDa (125aa), confirmed by MALDI-TOF
Concentration 0.25 mg/ml (determined by Bradford assay)
Form Liquid, in 20mM Tris-HCl buffer (pH 7.5) containing 0.2M NaCl, 50% glycerol, 5mM DTT
Purity > 85% by SDS-PAGE
Applications SDS-PAGE
NCBI Accession # NP_000631
Host E.coli
Tag His-tag
Storage Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
Intended Use For Research Use Only
References Fujisawa,T., et al. (2012) Int. J. Cancer 131 (2), 344-356
Barderas,R., et al. (2012) Cancer Res. 72 (11), 2780-2790

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