JDP2, 1-163aa, Human His tag

Catalog
01-P2068
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Proteins, Recombinant
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Product Name JDP2, 1-163aa, Human His tag
Background Jun dimerization protein 2, also known as JDP2, is a component of the AP-1 transcription factor that represses transactivation mediated by the Jun family of proteins. This protein is involved in a variety of transcriptional responses associated with AP-1 such as UV-induced apoptosis, cell differentiation, tumorigenesis and antitumogeneris. JDP2 can also function as a repressor by recruiting histone deacetylase 3/HDAC3 to the promoter region of JUN. It may control transcription via direct regulation of the modification of histones and the assembly of chromatin. Recombinant human JDP2 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
Synonyms Jun dimerization protein 2, JUNDM2
Species Human
Amino Acid Sequence MGSSHHHHHH SSGLVPRGSH MGSHMMPGQI PDPSVTTGSL PGLGPLTGLP SSALTVEELK YADIRNLGAM IAPLHFLEVK LGKRPQPVKS ELDEEEERRK RRREKNKVAA ARCRNKKKER TEFLQRESER LELMNAELKT QIEELKQERQ QLILMLNRHR PTCIVRTDSV KTPESEGNPL LEQLEKK
Molecular Weight 16.9 kDa(151aa) confirmed by MALDI-TOF
Concentration 0.5 mg/ml (determined by Bradford assay)
Form Liquid, in 20mM Tris-HCl buffer (pH8.0) containing 10% glycerol 1mM DTT
Purity > 90% by SDS-PAGE
Applications SDS-PAGE
NCBI Accession # NP_569736
Host E.coli
Tag His-tag
Storage Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
Intended Use For Research Use Only
References Kawaida R., et al. (2003) J. Exp. Med. 197:1029-1035
Jin C., et al. (2006) Nat. Struct. Mol. Biol. 13:331-338

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