| Product Name | KLK10, 34-276aa, Human |
|---|---|
| Description | KLK10, also known as Kallikrein-10, is one of the fifteen kallikrein subfamily members. Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. It is secreted and may play a role in suppression of tumorigenesis in breast and prostate cancers. Recombinant human KLK10 protein, fused to His-tag at N-terminus, was expressed in E.coli. |
| Synonyms | Kallikrein-10, NES1, PRSSL1 |
| Host | E.coli |
| Molecular Weight | 64.5 kDa (584aa) |
| Amino Acid Sequence |
MGSSHHHHHH SSGLVPRGSH MGSALLPQND TRLDPEAYGS PCARGSQPWQ VSLFNGLSFH CAGVLVDQSW VLTAAHCGNK PLWARVGDDH LLLLQGEQLR RTTRSVVHPK YHQGSGPILP RRTDEHDLML LKLARPVVLG PRVRALQLPY RCAQPGDQCQ VAGWGTTAAR RVKYNKGLTC SSITILSPKE CEVFYPGVVT NNMICAGLDR GQDPCQSDSG GPLVCDETLQ GILSWGVYPC GSAQHPAVYT QICKYMSWIN KVIRSN |
| Tag | His-tag |
| Reactivity | Human |
| Applications | SDS-PAGE |
| Form | Liquid, in 20mM Tris-HCl buffer (pH 8.0) containing 0.4M Urea, 10% glycerol |
| Concentration | 1 mg/ml (determined by Bradford assay) |
| Purity | > 85% by SDS-PAGE |
| Storage | Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles. |
| References |
Liu XL. et al. (1996) Cancer Res. 56:3371–3379. Zhang Y. et al. (2006) Biol. Chem. 387:715–721. |
| Supplier | ARP |
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