LAGE3, 1-143aa, Human

Proteins, Recombinant
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Product Name LAGE3, 1-143aa, Human
Background L antigen family member 3, also known as LAGE3, belongs to the CTAG family. Members of the LAGE/ESO gene family are clustered together on human chromosome Xq28 and have similar exon-intron structures. Unlike the other family members, which are normally expressed only in testis and activated in a wide range of human tumors, LAGE3 is ubiquitously expressed in somatic tissues. This protein is also highly conserved in mouse and rat, suggesting that the encoded protein is functionally important. Recombinant human LAGE3 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
Synonyms L antigen family member 3, CVG5, DXS9879E, DXS9951E, ESO3, ITBA2
Species Human
Molecular Weight 38.8 kDa (356aa) confirmed by MALDI-TOF
Concentration 0.25 mg/ml (determined by Bradford assay)
Form Liquid, in 20mM Tris-HCl buffer (pH 8.0) containing 0.15M NaCl, 30% glycerol, 1mM DTT, 0.1mM PMSF
Purity > 85% by SDS-PAGE
Applications SDS-PAGE
NCBI Accession # NP_006005
Host E.coli
Tag His-tag
Storage Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
Intended Use For Research Use Only
References Alpen B., et al. (2002) Gene. 297:141-149.

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