MAP1LC3B, 1-120aa, Human

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01-P0876
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Proteins, Recombinant
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Product Name MAP1LC3B, 1-120aa, Human
Background Microtubule-associated proteins 1A/1B light chain 3B, also known as MAP1LC3B, belongs to the MAP1 LC3 family. It is a subunit of neuronal microtubule-associated MAP1A and MAP1B proteins, which are involved in microtubule assembly and important for neurogenesis. MAP1LC3B may also be involved in formation of autophagosomal vacuoles. It is expressed primarily in heart, testis, brain and skeletal muscle. Recombinant human MAP1LC3B protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
Synonyms Microtubule-associated proteins 1A/1B light chain 3B, ATG8F, LC3B, MAP1A/1BLC3
Species Human
Amino Acid Sequence MGSSHHHHHH SSGLVPRGSH MPSEKTFKQR RTFEQRVEDV RLIREQHPTK IPVIIERYKG EKQLPVLDKT KFLVPDHVNM SELIKIIRRR LQLNANQAFF LLVNGHSMVS VSTPISEVYE SEKDEDGFLY MVYASQETFG
Molecular Weight 100.8kDa (912aa)
Concentration 0.5mg/ml (determined by Bradford assay)
Form Liquid, in 20mM Tris-HCl buffer (pH8.0) containing 10% glycerol, 2mM DTT, 100mM NaCl
Purity > 95% by SDS-PAGE
Applications SDS-PAGE
NCBI Accession # NP_073729
Host E.coli
Storage Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
Intended Use For Research Use Only
References Behrends C., et al. (2010) Nature. 466(7302):68-76.
Kabeya Y., et al. (2000) EMBO J. 19(21):5720-8.

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