MAX, 1-160aa, Human

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01-1821
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Proteins, Recombinant
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Product Name MAX, 1-160aa, Human
Background MAX is a member of the basic helix-loop-helix leucine zipper (bHLHZ) family of transcription factors. It is able to form homodimers and heterodimers with other family members, which include Mad, Mxi1 and Myc. Myc is an oncoprotein implicated in cell proliferation, differentiation and apoptosis. In contrast to Myc, which is highly regulated during progression through the cell cycle, Max is highly stable and is much more abundant than Myc. Recombinant human MAX protein, fused to His-tag at C-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
Synonyms bHLHd4, bHLHd5, bHLHd6, bHLHd7, bHLHd8, MYC associated factor X Helix loop helix zipper protein, MAX protein, MGC10775, MGC11225, MGC18164, MGC34679, MGC36767, Myc associated factor X, Myc binding novel HLH/LZ protein, Orf 1, Orf1, Protein max.
Species Human
Amino Acid Sequence MSDNDDIEVE SDEEQPRFQS AADKRAHHNA LERKRRDHIK DSFHSLRDSV PSLQGEKASR AQILDKATEY IQYMRRKNHT HQQDIDDLKR QNALLEQQVR ALEKARSSAQ LQTNYPSSDN SLYTNAKGST ISAFDGGSDS SSESEPEEPQ SRKKLRMEAS LEHHHHHH
Molecular Weight 25.3 kDa (235aa), confirmed by MALDI-TOF
Concentration 0.5 mg/ml (determined by Bradford assay)
Form Liquid, in 20mM Tris-HCl buffer (pH8.0) containing 10% glycerol 0.1M NaCl
Purity > 90% by SDS-PAGE
Applications SDS-PAGE
NCBI Accession # NP_002373
Host E.coli
Storage Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
Intended Use For Research Use Only
References Burbano HA., et al. (2010) Science. 328(5979):723-5.

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