MESDC2, 34-234aa, Human

Category: Proteins
Catalog
01-P0933
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Product Name MESDC2, 34-234aa, Human
Description MESDC2, also known as Mesoderm development candidate 2, is required for formation of the primitive streak and mesoderm during embryogenesis. This protein binds to the Wnt co-receptors LRP5 and LRP6 in the endoplasmic reticulum and is required for their proper folding and cell surface expression. Recombinant human MESDC2 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography.
Synonyms LDLR chaperone MESD, BOCA, KIAA0081, MESD
Host E.coli
Molecular Weight 13.6 kDa (122aa), confirmed by MALDI-TOF
Amino Acid Sequence MGSSHHHHHH SSGLVPRGSH MAEGSPGTPD ESTPPPRKKK KDIRDYNDAD MARLLEQWEK DDDIEEGDLP EHKRPSAPVD FSKIDPSKPE SILKMTKKGK TLMMFVTVSG SPTEKETEEI TSLWQGSLFN ANYDVQRFIV GSDRAIFMLR DGSYAWEIKD FLVGQDRCAD VTLEGQVYPG KGGGSKEKNK TKQDKGKKKK EGDLKSRSSK EENRAGNKRE DL
Tag His-tag
Reactivity Human
Applications SDS-PAGE
Form Liquid, in 20mM Tris-HCl buffer (pH8.0) containing 20% glycerol, 0.1M NaCl, 1mM DTT
Concentration 1.0 mg/ml (determined by BCA assay)
Purity > 90% by SDS-PAGE
Storage Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
References Kohler C, et al. (2006). J Struct Funct Genomics, 7:131-8.
Wines ME., et al. (2001). Genomics., 72:88-98.
Supplier ARP

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