Mouse PRMT1 isoform2, 1-353aa, Mouse, Recombinant

Catalog
01-2291
$0.00
-
+
Proteins, Recombinant
Questions? Contact Us
More Information
Product Name Mouse PRMT1 isoform2, 1-353aa, Mouse, Recombinant
Background Protein arginine N-methyltransferase 1(PRMT1) is a type I methyltransferase that transfers a methyl group from S-adenosylmethionine to guanidino nitrogens of arginine residues to form monomethylarginine and asymmetric dimethylarginine. Functions of type I arginine methylation in proteins may include regulation of transcription, modulation of the affinity of nucleic acid-binding proteins, regulation of interferon signaling pathways, and targeting of nuclear proteins. Mouse PRMT1(AAF37293) shares 99.9% sequence identity with the human proteins(NP_938074). Recombinant mouse PRMT1, fused to His-MBP tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
Synonyms Mrmt1, Hrmt112, AW214366, Protein arginine N-methytransferase 1, PRMT1 isoform2, PRMT1, Protein arginine N-methyltransferase 1 ANM 1, HCP 1, HMT1 hnRNP methyltransferase, Heterogeneous nuclear ribonucleoproteins methyltransferase like 2, HMT2, HRMT1 L2, HRMT1L 2, Heterogeneous nuclear ribonucleoproteins methyltransferase like2, HMT 2, HMT1 (hnRNP methyltransferase S, cerevisiae) like 2, HMT1 hnRNP methyltransferase like 2, HMT1 hnRNP methyltransferase like 2 (S, cerevisiae), Human mRNA for suppressor for yeast mutant, Human mRNA for suppressor for yeast mutant complete cds, Interferon receptor 1 bound protein 4, Interferon receptor 1 bound protein4, Interferon receptor 1bound protein 4, IR1 B4, IR1B 4, Mrmt 1, Mrmt1, PRMT 1, R1B4, S, cerevisiae like 2, Protein arginine N methyltransferase 1, Protein arginine N methyltransferase1,
Species Mouse
Amino Acid Sequence MHHHHHHMKI EEGKLVIWIN GDKGYNGLAE VGKKFEKDTG IKVTVEHPDK LEEKFPQVAA TGDGPDIIFW AHDRFGGYAQ SGLLAEITPD KAFQDKLYPF TWDAVRYNGK LIAYPIAVEA LSLIYNKDLL PNPPKTWEEI PALDKELKAK GKSALMFNLQ EPYFTWPLIA ADGGYAFKYE NGKYDIKDVG VDNAGAKAGL TFLVDLIKNK HMNADTDYSI AEAAFNKGET AMTINGPWAW SNIDTSKVNY GVTVLPTFKG QPSKPFVGVL SAGINAASPN KELAKEFLEN YLLTDEGLEA VNKDKPLGAV ALKSYEEELA KDPRIAATME NAQKGEIMPN IPQMSAFWYA VRTAVINAAS GRQTVDEALK DAQTNSSSNN NNNNNNNNLG IEGRGSHMAA AEAANCIMEV SCGQAESSEK PNAEDMTSKD YYFDSYAHFG IHEEMLKDEV RTLTYRNSMF HNRHLFKDKV VLDVGSGTGI LCMFAAKAGA RKVIGIECSS ISDYAVKIVK ANKLDHVVTI IKGKVEEVEL PVEKVDIIIS EWMGYCLFYE SMLNTVLHAR DKWLAPDGLI FPDRATLYVT AIEDRQYKDY KIHWWENVYG FDMSCIKDVA IKEPLVDVVD PKQLVTNACL IKEVDIYTVK VEDLTFTSPF CLQVKRNDYV HALVAYFNIE FTRCHKRTGF STSPESPYTH WKQTVFYMED YLTVKTGEEI FGTIGMRPNA KNNRDLDFTI DLDFKGQLCE LSCSTDYRMR
Molecular Weight 27 kDa (250 aa), confirmed by MALDI-TOF.
Concentration 1 mg/ml (determined by Bradford assay)
Form Liquid, in 25mM Tris pH 7.5, 1mM DTT, 1mM EDTA, 2mM beta-mercaptoethanol, 20% glycerol
Purity > 90% by SDS-PAGE
Applications SDS-PAGE
NCBI Accession # AAF37293
Host E.coli
Tag His-tag
Storage Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
Intended Use For Research Use Only
References Herrmann F., et al. (2005). J Biol Chem. 280(45):38005-10.
Abramovich C., et al. (1997). EMBO J. 16(2):260-6.

All Research Products are sold for laboratory RESEARCH USE ONLY and ARE NOT TO BE USED FOR HUMAN OR ANIMAL THERAPEUTIC OR DIAGNOSTIC APPLICATIONS. The information presented is believed to be accurate; however, said information and products are offered without warranty or guarantee since the ultimate conditions of use and the variability of the materials treated are beyond our control. Nothing disclosed herein is to be construed as a recommendation to use our products in violation of any patents. ARP American Research Products, Inc. does not submit its products for regulatory review by any government body or other organization, and we do not validate them for clinical, therapeutic or diagnostic use, or for safety and effectiveness. You are solely responsible for making sure that the way you use the products complies with applicable laws, regulations and governmental policies and for obtaining all necessary approvals, intellectual property rights, licenses and permissions that you may need related to your use. Under no circumstances shall ARP American Research Products, Inc. be liable for damages, whether consequential, compensatory, incidental or special, strict liability or negligence, breach of warranty or any other theory arising out of the use of the products available from ARP American Research Products, Inc. Nothing contained herein warrants that the use of the products will not infringe on the claims of any patents covering the product itself or the use thereof in combination with other products or in the operation of any process. ARP American Research Products, Inc. disclaims any and all representations or warranties of any kind whatsoever, express or implied, including without limitation any implied warranties of merchantability or fitness for a particular purpose, of non-infringement, or regarding results obtained through the use of any product, whether arising from a statute or otherwise in law or from a course of performance, dealing or usage of trade.

Hi, have questions?

An ARP Customer Service Representative is happy to help!

or Call (800) 832-2611