NIPSNAP1, 1-284aa, Human

Catalog
01-P2399
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Proteins, Recombinant
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Product Name NIPSNAP1, 1-284aa, Human
Background NIPSNAP1 is a member of the NipSnap family of proteins that may be involved in vesicular transport. A similar protein in mice inhibits the calcium channel TRPV6, and is also localized to the inner mitochondrial membrane where it may play a role in mitochondrial DNA maintenance. A pseudogene of this gene is located on the short arm of chromosome 17. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. Recombinant human NIPSNAP1 protein, fused to His-tag at N-terminus, was expressed in E.coli.
Synonyms Translational activator of cytochrome c oxidase 1
Species Human
Amino Acid Sequence MGSSHHHHHH SSGLVPRGSH MGSMAPRLCS ISVTARRLLG GPGPRAGDVA SAAAARFYSK DNEGSWFRSL FVHKVDPRKD AHSTLLSKKE
TSNLYKIQFH NVKPEYLDAY NSLTEAVLPK LHLDEDYPCS LVGNWNTWYG EQDQAVHLWR FSGGYPALMD CMNKLKNNKE YLEFRRERSQ
MLLSRRNQLL LEFSFWNEPQ PRMGPNIYEL RTYKLKPGTM IEWGNNWARA IKYRQENQEA VGGFFSQIGE LYVVHHLWAY KDLQSREETR
NAAWRKRGWD ENVYYTVPLV RHMESRIMIP LKISPLQ
Molecular Weight 23.4kDa (203aa) confirmed by MALDI-TOF
Concentration 0.25mg/ml (determined by Bradford assay)
Form Liquid, in 20mM Tris-HCl buffer (pH 8.0) containing 0.15M NaCl, 10% glycerol, 1mM DTT
Purity > 85% by SDS-PAGE
Applications SDS-PAGE
NCBI Accession # NP_003625
Host E.coli
Tag His-tag
Storage Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
Intended Use For Research Use Only
References Choudhary C., et al. (2009) Science. 325:834-840
Burkard T.R., et al. (2011) BMC Syst. Biol. 5:17-17

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