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|Product Name||NUDT16L1, 1-211aa, Human|
|Background||NUDT16L1, also known Syndesmos, is a cytoplasmic protein that interacts specifically with the cytoplasmic domain of syndecan-4, and it co-localizes with syndecan-4 in focal contacts. This protein interacts with the focal adhesion adaptor protein paxillin. The binding of syndesmos to paxillin is direct, and these interactions are triggered by the activation of protein kinase C. Recombinant human NUDT16L1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography.|
|Synonyms||Protein syndesmos, MGC11275, SDOS|
|Amino Acid Sequence||MGSSHHHHHH SSGLVPRGSH MSTAAVPELK QISRVEAMRL GPGWSHSCHA MLYAANPGQL FGRIPMRFSV LMQMRFDGLL GFPGGFVDRR FWSLEDGLNR VLGLGLGCLR LTEADYLSSH LTEGPHRVVA HLYARQLTLE QLHAVEISAV HSRDHGLEVL GLVRVPLYTQ KDRVGGFPNF LSNAFVSTAK CQLLFALKVL NMMPEEKLVE ALAAATEKQK KALEKLLPAS S|
|Molecular Weight||16.2 kDa (145aa), confirmed by MALDI-TOF|
|Concentration||1 mg/ml (determined by BCA assay)|
|Form||Liquid, in 20 mM Tris-HCl buffer (pH8.0) containing 0.2M NaCl, 2mM DTT, 40% glycerol|
|Purity||> 95% by SDS-PAGE|
|NCBI Accession #||NP_115725|
|Storage||Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.|
|Intended Use||For Research Use Only|
|References||Denhez F. et al. (2002) J. Biol. Chem. 277:12270-4.
Baciu PC. et al. (2000) J Cell Sci. 113:315-24.
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