NUDT9, 47-350aa, Human

Category: Proteins
Catalog
01-1884-9
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Product Name NUDT9, 47-350aa, Human
Description NUDT9 belongs to a superfamily of Nudix hydrolases. It is known to function as a highly specific adenosine diphosphate ribose pyrophosphatase that hydrolyzes ADP ribose to AMP and ribose 5'-phosphate. It has been suggested that NUDT9 may be involved in the regulation of the menstrual cycle and may be related to the proliferation of glandular cells in the human endometrium. Recombinant human NUDT9 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
Synonyms ADP-ribose pyrophosphatase, mitochondrial isoform a., MGC3037, NUDT10
Host E.coli
Molecular Weight 19.9 kDa (188aa), confirmed by MALDI-TOF
Amino Acid Sequence MGSSHHHHHH SSGLVPRGSH MNTNVMSGSN GSKENSHNKA RTSPYPGSKV ERSQVPNEKV GWLVEWQDYK PVEYTAVSVL AGPRWADPQI SESNFSPKFN EKDGHVERKS KNGLYEIENG RPRNPAGRTG LVGRGLLGRW GPNHAADPII TRWKRDSSGN KIMHPVSGKH ILQFVAIKRK DCGEWAIPGG MVDPGEKISA TLKREFGEEA LNSLQKTSAE KREIEEKLHK LFSQDHLVIY KGYVDDPRNT DNAWMETEAV NYHDETGEIM DNLMLEAGDD AGKVKWVDIN DKLKLYASHS QFIKLVAEKR DAHWSEDSEA DCHAL
Tag His-tag
Reactivity Human
Applications SDS-PAGE
Form Liquid, in 20mM Tris-HCl buffer (pH 8.0) containing 10% glycerol, 2mM DTT, 0.1M NaCl.
Concentration 1 mg/ml (determined by Bradford assay)
Purity > 95 % by SDS-PAGE
Storage Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
References Perraud AL., et al. (2001) Nature. 411(6837):595-9.
Perraud AL., et al. (2003) J Biol Chem. 278(3):1794-801.
Supplier ARP

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