| Product Name | NUTF2, 1-127aa, Human |
|---|---|
| Description | NUTF2 is a cytosolic factor that facilitates protein transport into the nucleus. It interacts with the nuclear pore complex glycoprotein p62 and Ran. This protein acts at a relative late stage of nuclear protein import, subsequent to the initial docking of nuclear import ligand at the nuclear envelope. It binds directly to RanGDP and may modulate the steady-state distribution of Ran. Recombinant human NUTF2, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography. |
| Synonyms | NTF2, Placental protein 15, PP15, Nuclear transport factor 2, NUTF 2, PP 15 |
| Host | E.coli |
| Molecular Weight | 26.5 kDa (236aa), confirmed by MALDI-TOF |
| Amino Acid Sequence | MGSSHHHHHH SSGLVPRGSH MGDKPIWEQI GSSFIQHYYQ LFDNDRTQLG AIYIDASCLT WEGQQFQGKA AIVEKLSSLP FQKIQHSITA QDHQPTPDSC IISMVVGQLK ADEDPIMGFH QMFLLKNIND AWVCTNDMFR LALHNFG |
| Tag | His-tag |
| Reactivity | Human |
| Applications | SDS-PAGE |
| Form | Liquid, in 20mM Tris-HCl buffer (pH 8.0) containing 1mM DTT, 10% glycerol |
| Concentration | 1mg/ml (determined by Bradford assay) |
| Purity | > 95% by SDS-PAGE |
| Storage | Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles. |
| References |
Gerace L., et al. (1995) J Cell Biol. 129(4):925-37. Tang SB., et al. (2009) Mol Vis. 15:861-9. |
| Supplier | ARP |
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