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|Product Name||Protein kinase Casein Kinase 2 alpha (PKCK2, 1-391aa) Human, Recombinantged|
|Background||Protein Kinase Casein Kinase 2 (PKCK2, also called CK2) is a ubiquitous Ser/Thr kinase expressed in all eukaryotes. PKCK2 is a tetramer composed of two catalytic kinase domains, alpha subunits, and two identical regulatory beta subunits. It has been implicated in cell cycle control, DNA repair, regulation of the circadian rhythm, and other cellular processes. Recombinant human PKCK2, fused to His tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.|
|Synonyms||CSNK2A1, CK2A1, Protein kinase Casein Kinase 2 alpha, PKCK2, CK II, EC 184.108.40.206, Casein kinase II subunit alpha, Casein kinase II alpha 1 subunit isoform a Casein kinase 2 alpha 1 polypeptide, Casein kinase II alpha 1 subunit, Casein kinase II alpha subunit, CK II, CK2 alpha, CK2 catalytic subunit alpha, CK2A1, CKII.|
|Amino Acid Sequence||MGSSHHHHHH SSGLVPRGSH MSGPVPSRAR VYTDVNTHRP REYWDYESHV VEWGNQDDYQ LVRKLGRGKY SEVFEAINIT NNEKVVVKIL KPVKKKKIKR EIKILENLRG GPNIITLADI VKDPVSRTPA LVFEHVNNTD FKQLYQTLTD YDIRFYMYEI LKALDYCHSM GIMHRDVKPH NVMIDHEHRK LRLIDWGLAE FYHPGQEYNV RVASRYFKGP ELLVDYQMYD YSLDMWSLGC MLASMIFRKE PFFHGHDNYD QLVRIAKVLG TEDLYDYIDK YNIELDPRFN DILGRHSRKR WERFVHSENQ HLVSPEALDF LDKLLRYDHQ SRLTAREAME HPYFYTVVKD QARMGSSSMP GGSTPVSSAN MMSGISSVPT PSPLGPLAGS PVIAAANPLG MPVPAAAGAQ Q|
|Molecular Weight||54 kDa (495 aa), confirmed by MALDI-TOF.|
|Concentration||1 mg/ml (determined by Bradford assay)|
|Form||Liquid, in Phosphate Buffered Saline pH7.4|
|Purity||> 90% by SDS-PAGE|
|NCBI Accession #||NP_001886|
|Storage||Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.|
|Intended Use||For Research Use Only|
|References||Kim YK., et al. (2006) J Biol Chem. 281(48):36752-7.|
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