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|Product Name||RAB8B, 1-204aa, Human|
|Background||RAB proteins, like RAB8B, are low molecular mass monomeric GTPases that localize on the cytoplasmic surfaces of distinct membrane-bound organelles. RAB proteins function in intracellular vesicle transport by aiding in the docking and/or fusion of vesicles with their target membranes. Recombinant human RAB8B protein, fused to His-tag at N-terminus, was expressed in E.coli.|
|Synonyms||Ras-related protein Rab-8B, 5930437D16, D330025I23Rik, FLJ38125, GTPase Rab8b, RAB 8b, RAB44|
|Amino Acid Sequence||MGSSHHHHHH SSGLVPRGSH MGSMAKTYDY LFKLLLIGDS GVGKTCLLFR FSEDAFNTTF ISTIGIDFKI RTIELDGKKI KLQIWDTAGQ ERFRTITTAY YRGAMGIMLV YDITNEKSFD NIKNWIRNIE EHASSDVERM ILGNKCDMND KRQVSKERGE KLAIDYGIKF LETSAKSSAN VEEAFFTLAR DIMTKLNRKM NDSNSAGAGG PVKITENRSK KTSFFRC|
|Molecular Weight||44.9kDa (410aa), confirmed by MALDI-TOF|
|Concentration||0.5mg/ml (determined by Bradford assay)|
|Form||Liquid, in 20mM Tris-HCl buffer (pH 8.0) containing 0.1M NaCl, 10% glycerol|
|Purity||> 90% by SDS-PAGE|
|NCBI Accession #||NP_057614|
|Storage||Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.|
|Intended Use||For Research Use Only|
|References||Chen D., et al. (1997) Biochim. Biophys. Acta. 1355:1-6
Hattula K., et al. (2002) Mol. Biol. Cell. 13:3268-3280
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