| Product Name | Recoverin, Human, Recombinant |
|---|---|
| Description | Recoverin is a heterogeneously acylated calcium-binding and intracellular signal transduction protein in the photoreceptor cells of retina. Recoverin contains four EF-hands, of which two bind Ca. Ca-induced extrusion of the acyl group from a hydrophobic cleft in the protein drives the translocation of recoverin from solution to the disc membrane. Recently, recoverin is a detectable serologic protein that is expressed in patients with cancer-associated retinopathy, a paraneoplastic syndrome. Recombinant human recoverin was overexpressed in E. coli and purified by using conventional chromatography techniques |
| Synonyms | RCVRN, RCV1, Recoverin, Cancer-associated retinopathy protein, Protein CAR, Recoverin, Cancer associated retinopathy protein, Cancer associated retinopathy protein antibody, CAR protein, |
| Host | E.coli |
| Molecular Weight | 21.4 kDa (192 aa), confirmed by MALDI-TOF. |
| Amino Acid Sequence | MGNSKSGALS KEILEELQLN TKFSEEELCS WYQSFLKDCP TGRITQQQFQ SIYAKFFPDT DPKAYAQHVF RSFDSNLDGT LDFKEYVIAL HMTTAGKTNQ KLEWAFSLYD VDGNGTISKN EVLEIVMAIF KMITPEDVKL LPDDENTPEK RAEKIWKYFG KNDDDKLTEK EFIEGTLANK EILRLIQFEP QKVKEKMKNA |
| Tag | His-tag |
| Reactivity | Human |
| Applications | SDS-PAGE |
| Form | Liquid, in 20mM Tris-HCl pH7.5, 2mM EDTA, 1mMDTT |
| Concentration | 1 mg/ml (determined by Bradford assay) |
| Purity | > 95% by SDS-PAGE |
| Storage | Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles. |
| References | Sampath P., et al. (2004) Cancer Control. 11, 174-80. Erickson MA., et al. (1998) Proc. Natl. Acad. Sci. 95, 6474-9. |
| Supplier | ARP |
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