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|Product Name||RhoB, 1-193aa, Human|
|Background||Rho-related GTP-binding protein RhoB, also known as RhoB, is a member of the Rho GTP-binding protein family. RhoB mediates apoptosis in neoplastically transformed cells after DNA damage. It plays a negative role in tumorigenesis as deletion causes tumor formation. Recombinant human RhoB protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.|
|Synonyms||Rho-related GTP-binding protein RhoB, ARH6, ARHB, MST081, MSTP081, RHOH6|
|Amino Acid Sequence||MGSSHHHHHH SSGLVPRGSH MAAIRKKLVV VGDGACGKTC LLIVFSKDEF PEVYVPTVFE NYVADIEVDG KQVELALWDT AGQEDYDRLR PLSYPDTDVI LMCFSVDSPD SLENIPEKWV PEVKHFCPNV PIILVANKKD LRSDEHVRTE LARMKQEPVR TDDGRAMAVR IQAYDYLECS AKTKEGVREV FETATRAALQ KRYGSQNGCI NCC|
|Molecular Weight||57.3 kDa (508aa) confirmed by MALDI-TOF|
|Concentration||0.25 mg/ml (determined by Bradford assay)|
|Form||Liquid, in phosphate-buffered saline (pH 7.4)|
|Purity||> 90% by SDS-PAGE|
|NCBI Accession #||NP_004031|
|Storage||Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.|
|Intended Use||For Research Use Only|
|References||Wennerberg K., et al. (2004) Journal of cell science 117 (Pt 8): 1301-12.
Wherlock M., et al (2004) J. Cell Sci. 117:3221-3231
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