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|Product Name||RRAS, 1-215aa, Human, Recombinant|
|Background||RRAS, also known as ras-related protein R-Ras, belongs to the Ras family which functions in signal transduction pathways. This protein has been shown to interact with RASSF5, NCK1, Bcl-2, ARAF and RALGDS. RRAS can bind GTP and GDP, and it has intrinsic GTPase activity. It also regulates the organization of the actin cytoskeleton. Recombinant RRAS protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.|
|Synonyms||, Ras-related protein R-Ras C86394, Oncogene RRAS2, Oncogene TC21, Ras like protein TC21, Ras related protein R Ras2, Related RAS viral (r ras) oncogene homolog 2, Related RAS viral oncogene homolog 2, RRAS 2, TC 21, TC21, Teratocarcinoma oncogene, Teratocarcinoma oncogene TC21.|
|Amino Acid Sequence||MGSSHHHHHH SSGLVPRGSH MSSGAASGTG RGRPRGGGPG PGDPPPSETH KLVVVGGGGV GKSALTIQFI QSYFVSDYDP TIEDSYTKIC SVDGIPARLD ILDTAGQEEF GAMREQYMRA GHGFLLVFAI NDRQSFNEVG KLFTQILRVK DRDDFPVVLV GNKADLESQR QVPRSEASAF GASHHVAYFE ASAKLRLNVD EAFEQLVRAV RKYQEQELPP SPPSAPRKKG GGCPC|
|Molecular Weight||23.6 kDa (205aa), confirmed by MALDI-TOF|
|Concentration||1 mg/ml (determined by Bradford assay)|
|Form||Liquid, in 20mM Tris-HCl buffer (pH 8.0) containing 10% glycerol 1mM DTT.|
|Purity||> 85% by SDS-PAGE|
|NCBI Accession #||NP_006261|
|Storage||Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.|
|Intended Use||For Research Use Only|
|References||Lowe DG. (1987) Cell. 48(1):137-46.|
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