S100A10, 1-97aa, Human

Catalog
01-2081A10
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Proteins, Recombinant
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Product Name S100A10, 1-97aa, Human
Background S100 calcium binding protein A10, also known S100A10, is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100A10 is primarily found in mast cells as heterotetrameric complexes that are present intracellularly at the plasma membrane or on the extracellular cell surface. Extracellular S100A10 is a key plasminogen receptor that plays an important role in cellular plasmin production and cellular invasiveness. Recombinant human S100A10 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
Synonyms S100 calcium binding protein A10, 42C, ANX2L, ANX2LG, CAL1, CLP11 GP11, p10, P11
Species Human
Amino Acid Sequence MGSSHHHHHH SSGLVPRGSH MPSQMEHAME TMMFTFHKFA GDKGYLTKED LRVLMEKEFP GFLENQKDPL AVDKIMKDLD QCRDGKVGFQ SFFSLIAGLT IACNDYFVVH MKQKGKK
Molecular Weight 39.5 kDa (346aa) confirmed by MALDI-TOF
Concentration 0.5 mg/ml (determined by Bradford assay)
Form Liquid, in 20mM Tris-HCl buffer (pH 8.0) containing 1mM DTT, 20% glycerol, 100mM NaCl
Purity > 90% by SDS-PAGE
Applications SDS-PAGE
NCBI Accession # NP_002957
Host E.coli
Tag His-tag
Storage Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
Intended Use For Research Use Only
References EI Rifai W., et al. (2000) Cancer Res. 62:6823-6826.
Gattaz W F., et al. (2000) Schizo Res. 43:91-5.

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