S100A14, 1-104aa, Human

Catalog
01-2081A14
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Proteins, Recombinant
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Product Name S100A14, 1-104aa, Human
Background S100A14 is a member of a subfamily of proteins related by EF-hand Ca2+ binding protein superfamily. The extracellular functions of the S-100 family may include the ability to enhance neurite outgrowth, involvement in inflammation, and motility of tumor cells. S100A14 contains 2 EF-hand Ca2+-binding domains, a myristoylation motif, a glycosylation site, and several potential protein kinase phosphorylation sites. It is expressed at high level in the colon and at moderate level in the thymus, kidney, liver, small intestine, and lung. Recombinant human S100A14 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
Synonyms S100 calcium binding protein A14, BCMP84, S100A15
Species Human
Amino Acid Sequence MGSSHHHHHH SSGLVPRGSH MGQCRSANAE DAQEFSDVER AIETLIKNFH QYSVEGGKET LTPSELRDLV TQQLPHLMPS NCGLEEKIAN LGSCNDSKLE FRSFWELIGE AAKSVKLERP VRGH
Molecular Weight 15.1 kDa (140aa) confirmed by MALDI-TOF
Concentration 0.5 mg/ml (determined by Bradford assay)
Form Liquid, in 20mM Tris-HCl buffer (pH 8.0) containing 10% glycerol, 1mM DTT, 0.1M NaCl.
Purity > 95% by SDS-PAGE
Applications SDS-PAGE
NCBI Accession # NP_065723
Host E.coli
Tag His-tag
Storage Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
Intended Use For Research Use Only
References Wright NT., et al. (2005) J Mol Biol. 353(2):410-26.
Zimmer DB., et al. (2005) Cell Mol Biol. 51(2):201-14.

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