| Product Name | SH3BGRL3, 1-93aa, Human |
|---|---|
| Description | SH3 domain-binding glutamic acid-rich-like protein 3, also known as SH3BGRL3, is located to chromosome 1p34.3-35 encodes for a small protein of 93 amino acids. SH3BGRL3 is the new member of thioredoxin (TRX) super family, whose posttranslational modified form was identified as tumor necrosis factor alpha (TNF-alpha) inhibitory protein. It may function as a regulator in all-trans retinoic acid-induced pathway. Recombinant human SH3BGRL3 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. |
| Synonyms | SH3 domain-binding glutamic acid-rich-like protein 3, SH3BP-1, TIP-B1 |
| Host | E.coli |
| Molecular Weight | 21.8 kDa (196aa) |
| Amino Acid Sequence | MGSSHHHHHH SSGLVPRGSH MGSMSGLRVY STSVTGSREI KSQQSEVTRI LDGKRIQYQL VDISQDNALR DEMRALAGNP KATPPQIVNG DQYCGDYELF VEAVEQNTLQ EFLKLA |
| Tag | His-tag |
| Reactivity | Human |
| Applications | SDS-PAGE |
| Form | Liquid, in 20mM Tris-HCl buffer (pH 8.0) containing 0.4M urea, 10% glycerol |
| Concentration | 1 mg/ml (determined by Bradford assay) |
| Purity | > 95% by SDS-PAGE |
| Storage | Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles. |
| References |
Mazzocco M., et al. (2002) Gene. 291:233-9 Xu C., et al. (2005) FEBS Lett. 579: 2788-94. |
| Supplier | ARP |
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