SHH, 24-197aa, Human

Catalog
01-2156
$0.00
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Proteins, Recombinant
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Product Name SHH, 24-197aa, Human
Background SHH, also known as Sonic hedgehog protein, is one of three proteins in the mammalian signaling pathway family called hedgehog. It plays a key role in regulating vertebrate organogenesis, such as in the growth of digits on limbs and organization of the brain. It controls cell division of adult stem cells and has been implicated in development of some cancers. Recombinant human SHH protein, fused to His-tag at C-terminus was expressed in E.coli and purified by using conventional chromatography techniques.
Synonyms HHG1, HLP3, HPE3, SMMCI, TPT, TPTPS, Sonic hedgehog protein HHG 1, HLP 3, Holoprosencephaly 3, HPE 3, MCOPCB5, SHH, SMMC I, SMMCI, Sonic Hedgehog (Drosophila) homolog, sonic hedgehog homolog (Drosophila), Sonic hedgehog homolog,
Species Human
Amino Acid Sequence MCGPGRGFGK RRHPKKLTPL AYKQFIPNVA EKTLGASGRY EGKISRNSER FKELTPNYNP DIIFKDEENT GADRLMTQRC KDKLNALAIS VMNQWPGVKL RVTEGWDEDG HHSEESLHYE GRAVDITTSD RDRSKYGMLA RLAVEAGFDW VYYESKAHIH CSVKAENSVA AKSGGLEHHH HHH
Molecular Weight 55.7 kDa (508aa), confirmed by MALDI-TOF
Concentration 0.5mg/ml (determined by Bradford assay)
Form Liquid, in Phosphate Buffered Saline pH7.4 containing 10% glycerol
Purity > 95% by SDS-PAGE
Applications SDS-PAGE
NCBI Accession # NP_000184
Host E.coli
Tag His-tag
Storage Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
Intended Use For Research Use Only
References Marigo V, et al. (1996) Proc Natl Acad Sci U S A. 93(18):9346-51
Kolpak A, et al. (2005) J Neurosci. 25(13):3432-41

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