SURF1, 80-273aa, Human

Catalog
01-1760-1
$0.00
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Proteins, Recombinant
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Product Name SURF1, 80-273aa, Human
Background SURF1, also known as surfeit 1, is a member of the SURF1 family, which includes the related yeast protein SHY1 and rickettsial protein RP733. This protein is localized to the inner mitochondrial membrane and thought to be involved in the biogenesis of the cytochrome c oxidase complex. Defect in SURF1 is a cause of Leigh syndrome, a severe neurological disorder that is commonly associated with systemic cytochrome c oxidase deficiency. Recombinant SURF1 protein was expressed in E.coli and purified by using conventional chromatography techniques.
Synonyms , Surfeit 1 SURF 1, SURF1, Surfeit locus protein 1,
Species Human
Amino Acid Sequence MGSSHHHHHH SSGLVPRGSH MQVQRRKWKL NLIAELESRV LAEPVPLPAD PMELKNLEYR PVKVRGCFDH SKELYMMPRT MVDPVREARE GGLISSSTQS GAYVVTPFHC TDLGVTILVN RGFVPRKKVN PETRQKGQIE GEVDLIGMVR LTETRQPFVP ENNPERNHWH YRDLEAMARI TGAEPIFIDA NFQSTVPGGP IGGQTRVTLR NEHLQ
Molecular Weight 37.8 kDa (333aa), confirmed by MALDI-TOF.
Concentration 1 mg/ml (determined by Bradford assay)
Form Liquid, in 20mM Tris-HCl buffer (pH 8.0) containing 10% glycerol, 1mM DTT, 0.1 M NaCl.
Purity > 95% by SDS-PAGE
Applications SDS-PAGE
NCBI Accession # NP_003163
Storage Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
Intended Use For Research Use Only
References Pequignot MO., et al. (2001) Hum Mutat. 17(5):374-81.
Zhu Z., et al. (1998) Nat Genet. 20(4):337-43.
Host E.coli

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