| Product Name | SYF2, 94-243aa, Human |
|---|---|
| Description | SYF2, also known as pre-mRNA-splicing factor SYF2, may be involved in pre-mRNA splicing. This protein interacts with cyclin D-type binding-protein 1, which is thought to be a cell cycle regulator at the G1/S transition. It is abundantly expressed in the heart, skeletal muscle and kidney and is expressed at lower levels in other tissues. Recombinant human SYF2 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by conventional chromatography, after refolding of the isolated inclusion bodies in a renaturation buffer. |
| Synonyms | Pre-mRNA-splicing factor SYF2, CBPIN, GCIPIP, p29 |
| Host | E.coli |
| Molecular Weight | 24.2 kDa (218aa) confirmed by MALDI-TOF (Molecular weight on SDS-PAGE will appear higher) |
| Amino Acid Sequence | MGSSHHHHHH SSGLVPRGSH MGSDYEKVKL LEISAEDAER WERKKKRKNP DLGFSDYAAA QLRQYHRLTK QIKPDMETYE RLREKHGEEF FPTSNSLLHG THVPSTEEID RMVIDLEKQI EKRDKYSRRR PYNDDADIDY INERNAKFNK KAERFYGKYT AEIKQNLERG TAV |
| Reactivity | Human |
| Applications | SDS-PAGE |
| Form | Liquid, in 20mM Tris-HCl buffer (pH8.0) containing 20% glycerol |
| Concentration | 0.25 mg/ml (determined by Bradford assay) |
| Purity | > 90% by SDS-PAGE |
| Storage | Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles. |
| References |
Chang M.-S., et al. (2000) Biochem. Biophys. Res. Commun. 279:732-737 Jurica M.S., et al. (2002) RNA. 8:426-439 |
| Supplier | ARP |
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