TFF1, 25-84aa, Human

Catalog
01-P1129
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Proteins, Recombinant
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Product Name TFF1, 25-84aa, Human
Background TFF1 (Trefoil factor 1) is member of trefoil family, characterized by having at least one copy of the trefoil motif, a 40-amino acid domain that contains three conserved disulfides. Trefoil peptides are protease resistant molecules secreted throughout the gut that play a role in mucosal healing. TFF1 has also been detected in a number of carcinomas including cancers of the breast, pancreas and stomach. Recombinant human TFF1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
Synonyms Trefoil factor 1, pS2, BCEI, HPS2, HP1.A, pNR-2
Species Human
Amino Acid Sequence MGSSHHHHHH SSGLVPRGSH MEAQTETCTV APRERQNCGF PGVTPSQCAN KGCCFDDTVR GVPWCFYPNT IDVPPEEECE F
Molecular Weight 19.6 kDa (174aa), confirmed by MALDI-TOF (Molecular weight on SDS-PAGE will appear higher)
Concentration 0.25 mg/ml (determined by Bradford assay)
Form Liquid, in 20mM Tris-HCl buffer (pH8.0) containing 20% glycerol, 1mM DTT
Purity > 90% by SDS-PAGE
Applications SDS-PAGE
NCBI Accession # NP_003216
Host E.coli
Tag His-tag
Storage Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
Intended Use For Research Use Only
References May FE., et al. (1997). J. Pathol. 183: 4-7.
Gott P, et al. (1997). Eur J Hum Genet 4 (6): 308-15.

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