TRAPPC2, 1-140aa, Human

Catalog
01-P1795
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Proteins, Recombinant
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Product Name TRAPPC2, 1-140aa, Human
Background TRAPPC2 is thought to be part of a large multi-subunit complex involved in the targeting and fusion of endoplasmic reticulum-to-Golgi transport vesicles with their acceptor compartment. In addition, this protein can bind c-myc promoter-binding protein 1 and block its transcriptional repression capability. Mutations in TRAPPC2 are a cause of spondyloepiphyseal dysplasia tarda (SEDT). Recombinant human TRAPPC2 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
Synonyms Trafficking protein particle complex subunit 2, hYP38334, MIP2A, SEDL, SEDT, TRAPPC2P1, TRS20, ZNF547L
Species Human
Amino Acid Sequence MGSSHHHHHH SSGLVPRGSH MGSMSGSFYF VIVGHHDNPV FEMEFLPAGK AESKDDHRHL NQFIAHAALD LVDENMWLSN NMYLKTVDKF NEWFVSAFVT AGHMRFIMLH DIRQEDGIKN FFTDVYDLYI KFSMNPFYEP NSPIRSSAFD RKVQFLGKKH LLS
Molecular Weight 39.7 kDa (351aa)
Concentration 1 mg/ml (determined by Bradford assay)
Form Liquid, in 20mM Tris-HCl buffer (pH 8.0) containing 0.4M urea, 10% glycerol
Purity > 90% by SDS-PAGE
Applications SDS-PAGE
NCBI Accession # NP_055378
Host E.coli
Tag His-tag
Storage Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
Intended Use For Research Use Only
References Gécz J, Shaw MA, et al. (2003). Gene. 27;320:137-44.

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