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|Product Name||TXNDC17, 1-123aa, Human|
|Background||TXNDC17, also known as thioredoxin domain-containing protein 17, is disulfide reductase. This protein may participate in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyze dithiol-disulfide exchange reactions. TXNDC17 has peroxidase activity and may contribute to the elimination of cellular hydrogen peroxide. Recombinant human TXNDC17 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography.|
|Synonyms||Thioredoxin domain-containing protein 17, TRP14, TXNL5|
|Amino Acid Sequence||MGSSHHHHHH SSGLVPRGSH MGSHMARYEE VSVSGFEEFH RAVEQHNGKT IFAYFTGSKD AGGKSWCPDC VQAEPVVREG LKHISEGCVF IYCQVGEKPY WKDPNNDFRK NLKVTAVPTL LKYGTPQKLV ESECLQANLV EMLFSED|
|Molecular Weight||21.0 kDa (190aa), confirmed by MALDI-TOF|
|Concentration||1.0 mg/ml (determined by Bradford assay)|
|Form||Liquid, in 20mM Tris-HCl buffer (pH8.0) containing 10% glycerol|
|Purity||> 95% by SDS-PAGE|
|NCBI Accession #||NP_116120|
|Storage||Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.|
|Intended Use||For Research Use Only|
|References||Jeong W., et al. (2004) J. Biol. Chem. 279:3142-3150
Jeong W., et al. (2004) J. Biol. Chem. 279:3151-3159
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