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|Product Name||UBL4A, 1-157aa , Human|
|Background||UBL4A, also known as GDX, contains 1 ubiquitin-like domain. Post-translational modification by ubiquitin and ubiquitin-related proteins plays critical roles in protein degradation and in regulation of essential cellular processes. In mammals, transcription grinds to a halt during late spermiogenesis due to compaction of the spermatid genome, which creates a special need for robust post-transcriptional regulation. UBL4A plays any role in targeting cellular proteins for degradation. Recombinant human UBL4A protein, fused to His-tag at C-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.|
|Synonyms||ubiquitin-like protein 4A, G6PD, GDX, GET5, MDY2, TMA24, UBL4|
|Amino Acid Sequence||MQLTVKALQG RECSLQVPED ELVSTLKQLV SEKLNVPVRQ QRLLFKGKAL ADGKRLSDYS IGPNSKLNLV VKPLEKVLLE EGEAQRLADS PPPQVWQLIS KVLARHFSAA DASRVLEQLQ RDYERSLSRL TLDDIERLAS RFLHPEVTET MEKGFSKLEH HHHHH|
|Molecular Weight||34.3 kDa (310aa) confirmed by MALDI-TOF|
|Concentration||1 mg/ml (determined by Bradford assay)|
|Form||Liquid, in 20mM Tris-HCl buffer (pH8.0) containing 20% glycerol, 0.1M NaCl, 1mM DTT|
|Purity||> 95% by SDS-PAGE|
|NCBI Accession #||NP_055050|
|Storage||Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.|
|Intended Use||For Research Use Only|
|References||Yang F, et al. (2007) Gene Expr Patterns. 7(1-2):131-6.
Mariappan M., et al. (2010) Nature 466:1120-1124
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