UBL4A, 1-157aa , Human

Proteins, Recombinant
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Product Name UBL4A, 1-157aa , Human
Background UBL4A, also known as GDX, contains 1 ubiquitin-like domain. Post-translational modification by ubiquitin and ubiquitin-related proteins plays critical roles in protein degradation and in regulation of essential cellular processes. In mammals, transcription grinds to a halt during late spermiogenesis due to compaction of the spermatid genome, which creates a special need for robust post-transcriptional regulation. UBL4A plays any role in targeting cellular proteins for degradation. Recombinant human UBL4A protein, fused to His-tag at C-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
Synonyms ubiquitin-like protein 4A, G6PD, GDX, GET5, MDY2, TMA24, UBL4
Species Human
Molecular Weight 34.3 kDa (310aa) confirmed by MALDI-TOF
Concentration 1 mg/ml (determined by Bradford assay)
Form Liquid, in 20mM Tris-HCl buffer (pH8.0) containing 20% glycerol, 0.1M NaCl, 1mM DTT
Purity > 95% by SDS-PAGE
Applications SDS-PAGE
NCBI Accession # NP_055050
Host E.coli
Tag His-tag
Storage Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
Intended Use For Research Use Only
References Yang F, et al. (2007) Gene Expr Patterns. 7(1-2):131-6.
Mariappan M., et al. (2010) Nature 466:1120-1124

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