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|Product Name||Vasostatin 2, 19-131aa, Human, Recombinant|
|Background||Vasostatin 2 is the N-terminal fragment (19-131 aa) derived from the cleavage of chromogranin A (CgA) which is a member of the chromogranin/secretogranin(granins) family of neuroendocrine secretory proteins. Vasostatin 2 has been shown to exert several biological activities on several tissues and organs and exerts a large spectrum of homeostatic actions, including antifungal and antimicrobial effect, modulation of cell adhesion, and inhibition of parathyroid hormone secretion. Recombinant human Vasostatin 2 protein was expressed in E.coli and purified by using conventional chromatography techniques.|
|Synonyms||Chromogranin A, Vasostatin 2, beta Granin, CGA, CHG A, CHGA, ChromograninA, Chromogranin A parathyroid secretory protein 1, Chromogranin A precursor, Pancreastatin, Parastatin, Parathyroid secretory protein 1, Pituitary secretory protein I, SP I, SP1, SPI, Vasostatin.|
|Amino Acid Sequence||MLPVNSPMNK GDTEVMKCIV EVISDTLSKP SPMPVSQECF ETLRGDERIL SILRHQNLLK ELQDLALQGA KERAHQQKKH SGFEDELSEV LENQSSQAEL KEAVEEPSSK DVME|
|Endotoxin Level||< 1.0 EU per 1 microgram of protein (determined by LAL method)|
|Molecular Weight||48.1 kDa (434aa), confirmed by MALDI-TOF.|
|Concentration||1 mg/ml (determined by BCA assay)|
|Form||Liquid, in 20 mM Tris-HCl buffer (pH 8.0) containing 10% glycerol,|
|Purity||> 95% by SDS-PAGE|
|NCBI Accession #||NP_001266|
|Storage||Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.|
|Intended Use||For Research Use Only|
|References||Tota BW., et al. (2008). Curr Med Chem. 15(14):1444-51
Blois A., et al. (2006). Requl pept. 134(1):30-7
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