Anti-NK1.1 / CD161bc (mouse) Monoclonal Antibody

Category: Antibodies
Catalog
1P-758-C100
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Product Name Anti-NK1.1 / CD161bc (mouse) Monoclonal Antibody
Description NK1.1 / CD161bc (also known as NKRP1, Ly55c, or Ly59) is a cell surface antigen expressed on NK cells and NK-T cells of certain mouse strains, which is being used for identification or antibody-mediated depletion of these cells in the respective strains. This antigen participates in NK cell activation, including production of interferon gamma, and release of cytotoxic granules. The reagent is designed for Flow Cytometry analysis of human blood cells using 10 μl reagent / 100 μl of whole blood or 106 cells in a suspension.The content of a vial (1 ml) is sufficient for 100 tests.
Clone PK136
Immunogen NK1-positive murine splenic and bone marrow cells
Isotype IgG2a
Specificity The mouse monoclonal antibody PK136 recognizes NK1.1 antigen (NK cell marker) expressed by some mouse strains (e.g. C57BL/6, NZB, CE, C58, Ma/My), whereas other strains (e.g. BALB/c, AKR, CBA, C3H) do not express this antigen. This antibody detects a conformational epitope on Nkrp1c and Nkrp1b gene products.
Reactivity Mouse
Applications FA, FC, IHC, IP
Form Phosphate buffered saline (PBS) with 15 mM sodium azide, approx. pH 7.4
Storage Store in the dark at 2-8°C. Do not freeze. Avoid prolonged exposure to light.
Supplier Exbio

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