TCP1 alpha Antibody: ATTO 700

Category: Antibodies
Catalog
SMC-479D-A700
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Product Name TCP1 alpha Antibody: ATTO 700
Description T-complex polypeptide-1 (TCP1) is a ~60 kDa protein constitutively expressed in almost all eukaryotic cells, and is up-regulated during spermatogenesis. It is found in the cytosol as a subunit of a hetero-oligomeric chaperone that is known to be involved in the folding of actin and tubulin. The family of proteins termed chaperonins act to recognize and stabilize polypeptide intermediates during folding, assembly and disassembly, and share many characteristics with Heat Shock Protein 70 (HSP 70) including high abundance, induction by environmental stress, and ATPase activity. The chaperonin family includes the mitochondrial HSP60, Escherichia coli GroEL, the plastid Rubisco-subunit binding protein, and the archaebacterial protein TF55. The TCP1 sequence shows nearly 40% identity to TF55, but only minimal similarity to HSP60 and GroEL. . Rat Anti-Mouse TCP1 alpha Monoclonal IgG2a
Synonyms p63 Antibody, Tcp-1 Antibody, TCP1 alpha Antibody, Ccta Antibody, TRic Antibody, Tp63 Antibody, 21454 Antibody, c-cpn Antibody, CCT Antibody, Tcp1 Antibody, ccpn Antibody, AI528772 Antibody, Cct1 Antibody, Tcp 1 Antibody, c cpn Antibody
Host Rat
Clone 91a
Immunogen Recombinant Mouse TCP1 alpha protein fragment (carboxy terminal region).
Isotype IgG2a
Specificity Detects ~60kDa. Also detects ~92kDa. Cross reactivity with human HSP60 has been observed with this antibody in immunoblot analysis. Reacts weakly with Saccharomyces cerevisiae, consistent with the epitope sequence being AKLRS (instead of AKLRA). In C. ele
Reactivity Bovine, Canine, Drosophila, Guinea Pig, Hamster, Human, Mouse, Porcine, Primate, Rabbit, Rat, Yeast, Parasite
Applications FCM, ICC, IF, IP, WB
Form Purified, in PBS pH7.4, 50% glycerol, 0.1% sodium azide
Gene Id NP_038714.2. 21454
Uniprot P11983
Supplier Stressmarq Biosciences

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