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|Product Name||TCTP, 1-172aa, Human|
|Background||TCTP, also known as Translationally controlled tumor protein, is regulated at the translational level. This protein is involved in calcium binding and microtubule stabilization. It is an immunoglobulin E dependent histamine-releasing factor produced by lymphocytes of atopic children and present in biologic fluids of allergic patients. Recombinant TCTP protein was expressed in E.coli and purified by using conventional chromatography techniques.|
|Synonyms||TPT1, HRF, p02, Fortilin, Histamine releasing factor, P23, Tumor protein translationally controlled 1.|
|AA Sequence||MRGSHHHHHH GMASMTGGQQ MGRDLYDDDD KDRWGSHMMI IYRDLISHDE MFSDIYKIRE IADGLCLEVE GKMVSRTEGN IDDSLIGGNA SAEGPEGEGT ESTVITGVDI VMNHHLQETS FTKEAYKKYI KDYMKSIKGK LEEQRPERVK PFMTGAAEQI KHILANFKNY QFFIGENMNP DGMVALLDYR EDGVTPYMIF FKDGLEMEKC|
|Molecular Weight||16.9 kDa (150aa), confirmed by MALDI-TOF.|
|Form||Liquid, in 20 mM Tris-HCl buffer (pH8.0) containing 1mM DTT, 0.1 M NaCl, and 10% glycerol|
|Concentration||0.5 mg/ml (determined by Bradford assay)|
|Purity||> 90% by SDS-PAGE|
|Storage||Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.|
|Intended Use||For Research Use Only|
|References||Sanchez JC., et al. (1997) Electrophoresis. 18(1):150-5.
Vonakis BM., et al. (2008) Blood. 111(4):1789-96.
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