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|Product Name||TNFRSF6B, 30-300aa, Human|
|Amino Acid Sequence||MGSSHHHHHH SSGLVPRGSH MGSVAETPTY PWRDAETGER LVCAQCPPGT FVQRPCRRDS PTTCGPCPPR HYTQFWNYLE RCRYCNVLCG
EREEEARACH ATHNRACRCR TGFFAHAGFC LEHASCPPGA GVIAPGTPSQ NTQCQPCPPG TFSASSSSSE QCQPHRNCTA LGLALNVPGS
SSHDTLCTSC TGFPLSTRVP GAEECERAVI DFVAFQDISI KRLQRLLQAL EAPEGWGPTP RAGRAALQLK LRRRLTELLG AQDGALLVRL
LQALRVARMP GLERSVRERF LPVH
|Background||TNFRSF6B belongs to Tumor necrosis factor receptor superfamily. It acts as a decoy receptor that competes with death receptors for ligand binding. This protein is postulated to play a regulatory role in suppressing FasL- and LIGHT-mediated cell death and T cell activation as well as to induce angiogenesis via neutralization of TL1A. Recombinant human TNFRSF6B protein, fused to His-tag at N-terminus, was expressed in E.coli.|
|Concentration||1mg/ml (determined by Bradford assay)|
|Form||Liquid, in 20mM Tris-HCl buffer (pH 8.0) containing 0.15M NaCl, 10% glycerol, 1mM DTT|
|Intended Use||For Research Use Only|
|Molecular Weight||33.6 kDa (303aa) confirmed by MALDI-TOF|
|NCBI Accession #||NP_003814|
|Purity||> 85% by SDS-PAGE|
|References||Pitti RM. et al. (1999) Nature. 396 : 699–703..
Yu KY. et al. (1999) J Biol Chem. 274: 13733–13736
|Storage||Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.|
|Synonyms||DCR3, DJ583P15.1.1, Decoy receptor 3, Decoy receptor for Fas ligand, M68, TR6|
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